Endocrine Abstracts

Background: Many chemicals present within the environment, as well as natural and artificial components of our diet, have the potential to interfere with the physiological role of hormones, interfering with hormone biosynthesis, signalling or metabolism. In the last years AMH, a protein secreted by granulosa cells, has emerged as a reliable marker of ovarian reserve. It is largely accepted the influence of age and smoking on AMH serum levels, although a clear effect of environ...

Background: HIV-infection is associated to several age-related comorbidities, such as a premature decline of serum testosterone (T). There is evidence about the relationship between health status, represented by frailty and comorbidities, and serum T levels in general population, while only one previous retrospective study investigated it in HIV-infected men.Aim: To investigate the association between frailty and gonadal status by assessing serum total T...

Background: HIV-infection is associated to premature decline of serum T. However, prevalence and biochemical characterization of hypogonadism in HIV-infected men are still to be well defined.Aim: To evaluate the gonadal status in HIV-infected men by assessing circulating total T (TT) with either ID-LC-MS/MS or CI.Methods: Prospective, cross-sectional, observational study on HIV-infected men with ongoing Highly Active Antiretroviral...

Background: ED is highly prevalent in HIV-infected men. T leads sexual behavior in men, but preliminary data suggests that ED is poorly related to serum T in HIV--infected men.Aim: To explore the relationship between sexual function and gonadal function in young/middle-aged HIV-infected men.Methodology: Prospective, cross-sectional, observational study on HIV-infected men (age <50 years). Serum TT was assessed by the gold stand...